Genetic structure of the nadA and nadB antivirulence loci in Shigella spp.

نویسندگان

  • Anne-Laure Prunier
  • Raymond Schuch
  • Reinaldo E Fernández
  • Anthony T Maurelli
چکیده

Comparison of nadA and nadB in 14 Shigella strains and enteroinvasive Escherichia coli versus E. coli showed that at least one locus is altered in all strains. These observations explain the characteristic nicotinic acid auxotrophy of Shigella organisms and are consistent with the previously identified antivirulence nature of these genes for these pathogens.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 189 17  شماره 

صفحات  -

تاریخ انتشار 2007